Archive for the 'health' Category

Diagnosis and Management of Autoimmune Cytopenias in Primary Immunodeficiency

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IDF 2021 PI Conference Session, “Diagnosis and Management of Autoimmune Cytopenias in Primary Immunodeficiency” was presented by Jolan Walter, MD, Ph.D. on June 26, 2021.
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Subtitles available in Spanish, French, Dutch, Danish, Arabic, Romanian, Chinese (Simplified), Portuguese and Italian.

What are primary immunodeficiencies?
The immune system helps your body fight infections. People with a primary immunodeficiency (PIDs, PI) or an inborn error of immunity (IEI), have immune systems that do not work properly.

PIDs are rare and chronic conditions that occur when some components of the immune system, mainly cells and proteins, do not work properly, or at all. People with PIDs are more prone than others to recurrent or unusual infections, and this can lead to serious harm to their health.

Primary immunodeficiencies manifest through many different symptoms, and recognizing these symptoms is key to an early and successful diagnosis. Importantly, patients also require different forms of medical treatments depending on their PID, and most of these are lifelong. Some PIDs can also be treated with curative interventions.

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Boosting Your Immune System Against Coronavirus | NBC News NOW

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Boosting Your Immune System Against Coronavirus | NBC News NOW

Dr. Mehmet Oz of “The Dr. Oz Show” explains ways you can boost your immune system against coronavirus.
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Boosting Your Immune System Against Coronavirus | NBC News NOW

Dermatologist’s Take on Eczema/Atopic dermatitis

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Annual World Primary Immunodeficiency Week and Covid-19

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A primary immunodeficiency disorder compromises the immune system and prevents the body from fighting off any infection or disease. During this time of Covid-19 a strong immune system is key and those who suffer from any immunodeficiency disease could be at an increased risk. The Annual World Primary Immunodeficiency Week has this year been extended to 10 weeks from 22 April to the 1st of July to raise awareness for those living with any of these diseases. Professor Claudia Gray, Paediatric Allergy Specialist at Red Cross Children’s Hospital & UCT Lung Institute joins us this morning to tell us more about the link between PID and Covid-19.

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HIV & AIDS – signs, symptoms, transmission, causes & pathology

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What are HIV and AIDS? HIV, or human immunodeficiency virus, is a virus that targets cells in the immune system. Over time, the immune system begins to fail which is called immunodeficiency, and this increases the risk of infections and tumors that a healthy immune system would usually be able to fend off. These complications are referred to as AIDS, or acquired immunodeficiency syndrome.

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Managing Gastrointestinal Complications

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IDF 2015 National Conference session, “Managing Gastrointestinal Complications” was presented by Dr. Jennifer Pate, MD on June 26, 2015.
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Quiz about Atopic Dermatitis, Eczema, and Noninfectious Immunodeficiency Disorders | Part 2

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31 quizzes about Atopic Dermatitis, Eczema, and Noninfectious Immunodeficiency Disorders – Part 2. Each quiz is an image for you to identify situations such as Pompholyx, Id reaction, Xerotic eczema, Nummular eczema, Job’s syndrome, Ataxia telangiectasia, Granulomatous lesions, Common variable immunodeficiency, Warts in DOCK8, Acute graft-versus-host disease, Acute graft-versus-host disease grade 2, Chronic graft-versus-host disease, Fasciitis in graft-versus-host disease, Sclerodermoid graft-versus-host disease, and more… All questions have answers.
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A Family Affair: One Family’s Journey with Severe Combined Immunodeficiency (SCID)

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Severe Combined Immunodeficiency (SCID) is a potentially fatal primary immunodeficiency. This condition is generally considered to be the most serious of the primary immunodeficiencies. Today, early identification of SCID can make possible life-saving interventions. Join the Immune Deficiency Foundation as we speak with Nicole Locastro, a mother of a child diagnosed with SCID through newborn screening. Nicole offers us some thoughtful insights into the family experience and some strategies her family employed along the way.

There's a misconception circulating that COVID-19 causes immunodeficiency. This is not the case

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There is a recent misconception circulating that COVID-19 causes immunodeficiency. The TL;DR: this is not the case.

Immunodeficiency occurs when one (or both) arms of the adaptive immune system are not functioning properly. This means that individuals become susceptible for a broad array of opportunistic illnesses. These include infections with microorganisms that would normally not cause disease in most healthy individuals.

These include:

Pneumocystis pneumonia: serious respiratory illness caused by fungal infection by the pathogen Pneumocystis jirovecii

Tuberculosis: caused by the bacterium Mycobacterium tuberculosis. Typically very rare, infection risk increases if someone’s immune system is not functioning properly.

Coccidioidomycosis: also called valley fever, this is another infection with a fungus found in the soil.

Cryptosporidiosis: a parasitic infection that can cause diarrhea and other severe GI symptoms

These types of illnesses are not occurring after recovery from COVID-19. T cells are not being “wiped out” after COVID-19. Yes, there is some evidence that some individuals have temporary immune system changes or perturbations after infection with SARS-CoV-2, but that is not the same as immunodeficiency, and is also not unique to this virus. More on this topic soon!

Winter respiratory illnesses such as RSV and influenza are not opportunistic infections. We’ve chatted about some reasons why there is increased infection activity previously, so check that out too.

Please be careful who you consume information from – misleading info is everywhere.

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Watch this IDF Forum recording to hear Alexandra Freeman, MD discuss COVID-19 and how it could affect people with primary immunodeficiency. This meeting was presented on April 13, 2020.
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107P Severe Combined Immunodeficiency, Wiskott Aldrich Syndrome

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Severe combined immunodeficiency (SCID) represents a constellation of genetically distinct syndromes with the common feature of defects in both humoral and cell-mediated immune responses. Affected infants are susceptible to severe recurrent infections by a wide array of pathogens, including bacteria, viruses, fungi, and protozoans; opportunistic infections by Candida, Pneumocystis, CMV, and Pseudomonas also cause serious (and occasionally lethal) disease.

Wiskott-Aldrich syndrome is an X-linked recessive disease characterized by thrombocytopenia, eczema, and a marked vulnerability to recurrent infection, ending in early death; the only treatment is bone marrow transplantation.