Wonder why your stomach still sticks out even though you're hammering the core exercises every day? It's a common myth that bulging belly is due to weak abdominal muscles. Some people can look fat with a bulging stomach even if they're not fat. It's called Bulging Belly Syndrome.
I recommend that you incorporate these 10 Simple Moves into your day. They take less than 15-minutes to complete.
Your immune system is critical for fighting off disease, but millions of people around the world are immunocompromised. This means their immune systems have been weakened either by a genetic disorder or by chronic illnesses like AIDS, Cancer or Diabetes. Living with such diseases is hard enough at the best of times, but in the age of COVID-19 a positive test could be a death sentence.
As nations race to get their populations vaccinated those with an already compromised immune system are often not at the top of the list. How can overburdened medical systems keep these at risk people from falling behind?
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Recent data suggested that about 3% of Americans are immunocompromised, according to ABC News contributor Dr. Alok Patel.
Chronic Diarrhea | Approach to Causes, Secretory vs Osmotic vs Inflammatory, Watery vs Bloody Diarrhea
Chronic diarrhea is diarrhea occurring for greater than 2-4 weeks, and it is broadly categorized into secretory, osmotic, functional, inflammatory, and malabsorptive causes. Causes include medications, crohn’s disease and celiac disease among many others. Depending on the cause, we can see either watery diarrhea or bloody diarrhea, or diarrhea with or without food. In this lesson, we look at an approach to the cause of chronic diarrhea, including a variety of factors that can help determine the cause of chronic diarrhea.
I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one!
JJ
**MEDICAL LEGAL DISCLAIMER**: JJ Medicine does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.
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Common Variable Immunodeficiency (CVID)
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Common variable immunodeficiency (CVID) is a primary immune deficiency disease characterized by low levels of protective antibodies and an increased risk of infections. Although the disease usually is diagnosed in adults, it also can occur in children. CVID also is known as hypogammaglobulinemia, adult-onset agammaglobulinemia, late-onset hypogammaglobulinemia, and acquired agammaglobulinemia.
NIAID supports research to determine genetic causes of CVID that may lead to therapeutic approaches to address the disease. Researchers also are exploring how antibody-based drugs may lessen the severity of the condition.
Causes
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CVID is caused by a variety of different genetic abnormalities that result in a defect in the capability of immune cells to produce normal amounts of all types of antibodies. Only a few of these defects have been identified, and the cause of most cases of CVID is unknown. Many people with CVID carry a DNA variation called a polymorphism in a gene known as TACI. However, while this genetic abnormality confers increased risk of developing CVID, it alone is not capable of causing CVID.
CVID is also linked to IgA deficiency, a related condition in which only the level of the antibody immunoglobulin A (IgA) is low, while levels of other antibody types are usually normal or near normal. IgA deficiency typically occurs alone, but in some cases it may precede the development of CVID or occur in family members of CVID patients.
Symptoms & Diagnosis
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People with CVID may experience frequent bacterial and viral infections of the upper airway, sinuses, and lungs. Acute lung infections can cause pneumonia, and long-term lung infections may cause a chronic form of bronchitis known as bronchiectasis, which is characterized by thickened airway walls colonized by bacteria.
People with CVID also may have diarrhea, problems absorbing food nutrients, reduced liver function, and impaired blood flow to the liver. Autoimmune problems that cause reduced levels of blood cells or platelets also may occur. People with CVID may develop an enlarged spleen and swollen glands or lymph nodes, as well as painful swollen joints in the knee, ankle, elbow, or wrist. In addition, people with CVID may have an increased risk of developing some cancers.
Doctors can diagnose CVID by weighing factors including infection history, digestive symptoms, lab tests showing very low immunoglobulin levels, and low antibody responses to immunization.
Treatment
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CVID is treated with intravenous immunoglobulin infusions or subcutaneous (under the skin) immunoglobulin injection to partially restore immunoglobulin levels. The immunoglobulin given by either method provides antibodies from the blood of healthy donors. The frequent bacterial infections experienced by people with CVID are treated with antibiotics. Other problems caused by CVID may require additional, tailored treatments.
Rheumatoid arthritis is a chronic inflammatory disorder that can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels.
An autoimmune disorder, rheumatoid arthritis occurs when your immune system mistakenly attacks your own body’s tissues. Video Rating: / 5
This video “Primary Immunodeficiency” is part of the Lecturio course “Immunology” ► WATCH the complete course on http://lectur.io/primaryimmunodeficiency
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Severe combined immunodeficiency (SCID) is a group of rare disorders caused by mutations in different genes involved in the development and function of infection-fighting immune cells. Infants with SCID appear healthy at birth but are highly susceptible to severe infections.
Severe combined immunodeficiency – A deadly combination of defects of T & B lymphocytes + Natural killer cells
Its a primary immunodeficiency (inherited in the family) affecting T lymphoocytes, B lymphocytes and Natural killer cells in different combinations.
These children die within one year without a bone marrow transplantation.There have been cases like “David the bubble boy” who survived for 12 years in a sterile chamber isolated from pathogens.
Patients are small babies that suffers from fungal, bacterial, or viral infections since their immune system is not functioning as it should.
The symptoms can be:
recurrent infections resistant to antibiotics,
failure to thrive with abnormal growth curves,
diarrhea,
diaper rash,
bronchitis,
pneumonia,
otitis media,
liver abscess,
morbilliform rash,
oral candidiasis
Doctors can check the sequence of DNA to determine any mutations that would cause this disease.
One have to remember that the levels of antibodies decline after about 6 month of age if the baby fails to produce new ones for himself, since the antibodies from the mother are depleted.
So these babies may appear healthy for about 6 months.
Therefore we can check blood values of lymphocytes, natural killer cells and antibodies to easier determine which type of Severe combined immunodeficiency we are dealing with.
What are the types of this disease?
Mainly X linked recessive (IL2RG gene mutation at Xq13.1) and autosomal recessive .
The autosomal recessive have many types:
adenosine deaminase deficiency,
Jak3 intracellular kinase mutation,
Purine nucleoside phosphorylase mutation,
Omenn syndrome with RAG gene mutation,
Bare lymphocyte syndrome with MHC 2 gene mutation.
The adenosine deaminase deficiency cause an accumulation of dATP, which blocks the enzyme Ribonucleotide reductase (converts NDP to dNDP). Without dNDP there is no DNA synthesis and therefore no production of cells like T & B lymphocytes.
You can imagine that without T & B cells there is no real immunity against infections. We can see depleted zones in the hypoplastic lymphoid organs. One example being a small thymus lacking lymphocytes and Hassall’s corpuscles. On X-ray there is an abscence of thymic shadow.
The treatment?
Bone marrow transplantation and gene therapy. About 1 patient out of 5 have a risk of getting acute T cell leukemia when treated with bone marrow transplantation.
These videos are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Nordic Health Organization video. Video Rating: / 5
The Social Determinants of Health are the conditions in which people are born, grow, live and age. They have a large influence on our health. It also determines health inequities, which is the unfair and avoidable health difference between different groups of people In this video we take a look at the social determinants of health..what they are, how it impacts health and a useful framework to understand it.
This video was created by Ranil Appuhamy
Voiceover – James Clark
For more information have a look at these resources:
http://www.who.int/social_determinants/en/
http://www.who.int/social_determinants/thecommission/en/
https://www.cdc.gov/socialdeterminants/
http://www.ucl.ac.uk/whitehallII
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Disclaimer:
These videos are provided for educational purposes only. Users should not rely solely on the information contained within these videos and is not intended to be a substitute for advice from other relevant sources. The author/s do not warrant or represent that the information contained in the videos are accurate, current or complete and do not accept any legal liability or responsibility for any loss, damages, costs or expenses incurred by the use of, or reliance on, or interpretation of, the information contained in the videos. Video Rating: / 5
This video is a 4-minute summary of the Determinants of Health! Determinants are factors that can influence a person’s health. While the focus of health interventions has typically been, who people are and what they do, the conditions in which they are born, grow, live, work and age are critically important in determining the health of individuals and communities.
Created by Dr Ranil Appuhamy
Voice over by James Clark
References/Further reading:
1. WHO definition of Health: https://www.who.int/about/who-we-are/constitution
2. WHO Social Determinants of Health: https://www.who.int/social_determinants/en/
3. Australia’s Health: https://www.aihw.gov.au/reports/australias-health/australias-health-2018/contents/table-of-contents
4. WHO: Country Statistics: https://www.who.int/countries/sle/en/
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Disclaimer: These videos are provided for educational purposes only. Users should not rely solely on the information contained within these videos and is not intended to be a substitute for advice from other relevant sources. The author/s do not warrant or represent that the information contained in the videos are accurate, current or complete and do not accept any legal liability or responsibility for any loss, damages, costs or expenses incurred by the use of, or reliance on, or interpretation of, the information contained in the videos.
NOTE FROM TED: Please consult with a mental health professional and do not look to this talk for medical advice as the intersection of mental health and nutrition is still an emerging field of study. We’ve flagged this talk for falling outside TEDx’s curatorial guidelines because it oversimplifies interpretations of legitimate studies. TEDx events are independently organized by volunteers. The guidelines we give TEDx organizers are described in more detail here: http://storage.ted.com/tedx/manuals/tedx_content_guidelines.pdf
This talk was given at a local TEDx event, produced independently of the TED Conferences. In this critically important talk, clinical psychologist Julia Rucklidge explores a range of scientific research, including her own, showing the significant role played by nutrition in mental health or illness.
Julia J Rucklidge, PhD is a Professor of Clinical Psychology in the Department of Psychology at the University of Canterbury, Christchurch, New Zealand. Originally from Toronto, she did her training in neurobiology (McGill) and Clinical Psychology (University of Calgary). Her interests in nutrition and mental illness grew out of her own research showing poor outcomes for children with significant psychiatric illness despite receiving conventional treatments for their conditions. For the last 6 years, she has been investigating the role of micronutrients in the expression of mental illness, specifically ADHD, Bipolar Disorder, anxiety and more recently, stress and PTSD associated with the Canterbury earthquakes.
About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
